Article
NPHS2 mutations in children with steroid-resistant nephrotic syndrome.
Iranian journal of kidney diseases - 1 Apr 2009
Otukesh Hasan, Ghazanfari Behzad, Fereshtehnejad Seyed-Mohammad, Bakhshayesh Masoomeh, Hashemi Mehrdad, Hoseini Rozita, Chalian Majid, Salami Arezoo, Mehdipor Leila, Rahiminia Aysan
Abstract excerpt
INTRODUCTION: Congenital nephrotic syndrome may be caused by mutations in NPHS1 and NPHS2, which encode nephrin and podocin, respectively. Since the identification of the NPHS2 gene, various investigators have demonstrated that its mutation is an important cause of steroid-resistant nephrotic syndrome. We aimed to evaluate frequency and spectrum of podocin mutations in the Iranian children with steroid-resistant...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.