Article
Molecular basis of steroid-resistant nephrotic syndrome.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia - 1 Jan 2005
Antignac C
Abstract excerpt
The identification of the underlying gene defect in some cases of steroid resistant nephrotic syndrome (SRNS) has recently led to a critical breakthrough in the understanding of the pathogenesis of nephrotic syndromes. The more severe form of hereditary nephrotic syndromes is the congenital nephrotic syndrome of the Finnish type (CNF). The causative gene, NPHS1, encodes a novel protein, nephrin which is a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.