Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Staphylococcus aureus plasmid that specifies constitutive macrolide-lincosamide-streptogramin B resistance contains a novel deletion in the ermC attenuator.

FEMS microbiology letters - 1 May 1990

Catchpole I, Dyke K G

Abstract excerpt

A 2.5 kb plasmid, pA22, isolated from a naturally occurring S. aureus strain confers constitutive MLS-resistance. By restriction enzyme analysis, pA22 is indistinguishable from the S. aureus inducible MLS-resistance conferring plasmid, pT48, apart froma small deletion. DNA sequencing showed that the deletion, is in the leader/attenuator region of the ermC (MLS-resistance) gene and removes some of the...

Topics

Amino Acid Sequence
Anti-Bacterial Agents
Base Sequence
DNA, Bacterial
Drug Resistance, Microbial
Erythromycin
Gene Expression Regulation, Bacterial
Genes, Bacterial
Lincosamides
Macrolides
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nucleic Acid Conformation

R Factors

Staphylococcus aureus

Virginiamycin

Source

Identifiers

PMID: 2116351
DOI: 10.1016/0378-1097(90)90410-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2116351-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Staphylococcus aureus plasmid that specifies constitutive macrolide-lincosamide-streptogramin B resistance contains a novel deletion in the ermC attenuator.PMID 2116351Read ↗

Plasmid‐mediated resistance to protein biosynthesis inhibitors in staphylococciSemantic proximity Read ↗

Plasmid-Mediated Antimicrobial Resistance in Staphylococci and Other Firmicutes.Semantic proximity Read ↗

Molecular analysis of constitutively expressed erm(C) genes selected in vitro by incubation in the presence of the noninducers quinupristin, telithromycin, or ABT-773.Semantic proximity Read ↗

Characterization of plasmids that confer inducible resistance to 14-membered macrolides and streptogramin type B antibiotics in Staphylococcus aureus.Semantic proximity Read ↗

Replication of Staphylococcal Resistance PlasmidsSemantic proximity Read ↗

A dyadic plasmid that shows MLS and PMS resistance in Staphylococcus aureus.Semantic proximity Read ↗

Minimal functional system required for expression of erythromycin resistance by msrA in Staphylococcus aureus RN4220.Semantic proximity Read ↗

Replication mutants of Staphylococcus aureus macrolide-lincosamide-streptogramin B resistance plasmid pT48.Semantic proximity Read ↗

Unusual inducible cross resistance to macrolides, lincosamides, and streptogramins B by methylase production in clinical isolates of Staphylococcus aureus.Semantic proximity Read ↗

Characterization of the spontaneous elimination of streptomycin sensitivity (SmS) on high-copy-number plasmids: SmS-enforcement cloning vectors with a synthetic rpsL gene.Semantic proximity Read ↗

A plasmid that encodes three genes for resistance to macrolide antibiotics in<i>Staphylococcus aureus</i>Semantic proximity Read ↗

Spontaneous deletions isolated from a triintegrate plasmid in Staphylococcus aureus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.