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Article

PI-3-Kinase inhibitors in colorectal cancer.

Current cancer drug targets - 1 Feb 2011

Ihle N T, Powis G, Kopetz S

Abstract excerpt

Despite recent successes, metastatic colorectal cancer remains a difficult cancer to treat. Since the initial discovery that PI-3-Kinase/AKT signaling played an important part in the growth and survival of colorectal tumors, preclinical studies have suggested that inhibitors of this pathway may have a role to play as potential therapeutics. With the surge of inhibitors of PI-3-Kinase from both academia and...

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Source

Identifiers

PMID: 21158718
DOI: 10.2174/156800911794328448

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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