Article
New phosphatidylinositol 3-kinase inhibitors for cancer.
Expert opinion on investigational drugs - 1 Apr 2011
Bowles Daniel W, Jimeno Antonio
Abstract excerpt
INTRODUCTION: Cancer treatment is moving away from conventional cytotoxic drugs and towards agents that target specific proteins important to cancer development or survival. The PI3K signaling axis is an important pathway involved in myriad human malignancies. Inhibition of this axis is a promising therapeutic approach for several cancers. AREAS COVERED: This article reviews current literature and recent...
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