Article
Baseline prediction of combination therapy outcome in hepatitis C virus 1b infected patients by discriminant analysis using viral and host factors.
PloS one - 30 Nov 2010
Saludes Verónica, Bracho Maria Alma, Valero Oliver, Ardèvol Mercè, Planas Ramón, González-Candelas Fernando, Ausina Vicente, Martró Elisa
Abstract excerpt
BACKGROUND: Current treatment of chronic hepatitis C virus (HCV) infection has limited efficacy -especially among genotype 1 infected patients-, is costly, and involves severe side effects. Thus, predicting non-response is of major interest for both patient wellbeing and health care expense. At present, treatment cannot be individualized on the basis of any baseline predictor of response. We aimed to identify...
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