Article
Increased serum levels of neutrophil gelatinase-associated lipocalin in patients with essential thrombocythemia and polycythemia vera.
Leukemia & lymphoma - 1 Jan 2011
Allegra Alessandro, Alonci Andrea, Bellomo Giacomo, Campo Salvatore, Cannavò Antonino, Penna Giuseppa, Russo Sabina, Centorrino Raffaella, Gerace Demetrio, Petrungaro Annamaria, Musolino Caterina
Abstract excerpt
Neutrophil gelatinaase-associated lipocalin (NGAL) is a glycoprotein bound with matrix metalloproteinase-9 (MMP-9) in human neutrophils, and elevated tissue NGAL expression has been documented in different infectious and inflammatory conditions. Recent evidence suggests that NGAL expression is induced in many types of human cancer. Moreover, NGAL is required for BCR-ABL-induced tumorigenesis. The aim of the...
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