Article
Keratinocyte growth factor gene transduction ameliorates pulmonary fibrosis induced by bleomycin in mice.
American journal of respiratory cell and molecular biology - 1 Sept 2011
Sakamoto Seiko, Yazawa Takuya, Baba Yasuko, Sato Hanako, Kanegae Yumi, Hirai Toyohiro, Saito Izumu, Goto Takahisa, Kurahashi Kiyoyasu
Abstract excerpt
Pulmonary fibrosis has high rates of mortality and morbidity, but there is no established therapy at present. We demonstrate here that bleomycin-induced pulmonary fibrosis in mice is ameliorated by intratracheal administration of keratinocyte growth factor (KGF)-expressing adenovirus vector. Prog...
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