Article
Performance of single nucleotide polymorphisms versus haplotypes for genome-wide association analysis in barley.
PloS one - 22 Nov 2010
Lorenz Aaron J, Hamblin Martha T, Jannink Jean-Luc
Abstract excerpt
Genome-wide association studies (GWAS) may benefit from utilizing haplotype information for making marker-phenotype associations. Several rationales for grouping single nucleotide polymorphisms (SNPs) into haplotype blocks exist, but any advantage may depend on such factors as genetic architecture of traits, patterns of linkage disequilibrium in the study population, and marker density. The objective of this...
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