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Article

Effects of genetic variations in the dopaminergic system on fatigue in humans: gender aspects.

Bulletin of experimental biology and medicine - 1 Aug 2010

Malyuchenko N V, Schegolkova J V, Kulikova M A, Timofeeva M A, Shlepzova V A, Sysoeva O V, Ivanitsky A M, Tonevitsky A G

Abstract excerpt

Changes in the functional status under the effect of intense mental exercise were studied in carriers of different variants of DAT1, DRD2, and COMT genes. The volunteers (n=140) performed 3-h monotonous mental work (information processing and logical problem solving). The degree of fatigue was evaluated before and after exercise by the HAM (Health status-Activity-Moods) and AMF (Acute Mental Fatigue)...

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Source

Identifiers

PMID: 21113497
DOI: 10.1007/s10517-010-0913-4

Genes

COMT
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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