Article
[Human intra-intronic minisatellite UPS29 associated with neurological diseases regulates reporter gene EGFP expression depending on cell type].
Tsitologiia - 1 Jan 2010
Sasina L K, Slominskaia N A, Suchkova I O, Pitsik E V, Solov'ev K V, Grudinina N A, Klinskaia T A, Patkin E L
Abstract excerpt
Earlier, it was established that polymorphism of minisatellite UPS29 located in one of introns of human gene CENTB5 (ACAP3) was associated with Parkinson's disease and epilepsy. The main aim of this work was to elucidate if that minisatellite could regulate reporter gene activity, and if such activity was tissue (cell)-specific. To this end there was used transient transfection of HeLa cells, mouse embryonal...
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