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Article

A transferable plasmid associated with AS-48 production in Enterococcus faecalis.

Journal of bacteriology - 1 May 1990

Martínez-Bueno M, Gálvez A, Valdivia E, Maqueda M

Abstract excerpt

Enterococcus faecalis S-48 produces a peptide antibiotic, AS-48, and a bacteriocin, Bc-48. We have isolated mutants that lack these inhibitory characteristics. Further analysis of the mutants indicates that a plasmid of 56 kilobases (pMB2) may harbor the genes for AS-48. In conjugation experiments, pMB2 has been transferred into a plasmid-free OG1X strain of E. faecalis. The OG1X(pMB2) transconjugant produces the...

Topics

Anti-Bacterial Agents
Bacterial Proteins
Conjugation, Genetic
DNA, Bacterial
Enterococcus faecalis
Escherichia coli
Mutation
Peptides
Phenotype
Plasmids

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Identifiers

PMID: 2110152
DOI: 10.1128/jb.172.5.2817-2818.1990
PMCID: PMC208938

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2110152-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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