Article
[Genetic diversity of X-chromosome in populations of aboriginal Siberian ethnic groups: linkage disequilibrium structure and haplotype philogeography of ZFX locus].
Molekuliarnaia biologiia - 1 Jan 2000
Khitrinskaia I Iu, Khar'kov V N, Stepanov V A
Abstract excerpt
The structure of gene pool of the Siberian aboriginal population has been described based on the data on polymorphism of ZFX gene located on X-chromosome. In ten populations under study 49 haplotypes have been determined, three of which are presented with high frequency. Comparing the obtained results with the available data from HapMap project unique "African" haplotypes were revealed, which occurred in Yoruba...
Topics
- Chromosomes, Human, X
- Female
- Genetics, Medical
- Humans
- Kruppel-Like Transcription Factors
- Linkage Disequilibrium
- Male
- Phylogeography
- Polymorphism, Single Nucleotide
- Quantitative Trait Loci
- Siberia
