Article
Impact of MHC class II polymorphism on blood counts of CD4+ T lymphocytes in macaque.
Immunogenetics - 1 Feb 2011
Aarnink Alice, Garchon Henri-Jean, Puissant-Lubrano Bénédicte, Blancher-Sardou Marie, Apoil Pol-André, Blancher Antoine
Abstract excerpt
While the number of peripheral blood T lymphocytes and of their two main subsets (CD4+CD8- and CD4-CD8+) varies little in a given healthy individual, substantial variation is observed between individuals. It was proposed that these counts could be influenced by MHC polymorphisms because of the well-established role of MHC molecules in thymic T lymphocyte maturation and presentation of antigenic peptides to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
