Article
A Q63E Rhodobacter sphaeroides AppA BLUF domain mutant is locked in a pseudo-light-excited signaling state.
Biochemistry - 21 Dec 2010
Dragnea Vladimira, Arunkumar Alphonse I, Lee Chul Won, Giedroc David P, Bauer Carl E
Abstract excerpt
The AppA BLUF photoreceptor from Rhodobacter sphaeroides contains a conserved key residue, Gln63, that is thought to undergo a shift in hydrogen-bonding interactions when a bound flavin is light excited. In this study we have characterized two substitution mutants of Gln63 (Q63E, Q63L) in the con...
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