Article
C-MYC rearrangement may induce an aggressive phenotype in anaplastic lymphoma kinase positive anaplastic large cell lymphoma: Identification of a novel fusion gene ALO17/C-MYC.
American journal of hematology - 1 Jan 2011
Moritake Hiroshi, Shimonodan Hidemi, Marutsuka Kousuke, Kamimura Sachiyo, Kojima Hitomi, Nunoi Hiroyuki
Abstract excerpt
Anaplastic lymphoma kinase (ALK) positive anaplastic large cell lymphoma (ALCL) is usually associated with a favorable prognosis. We describe an 11-year-old girl patient with ALK positive ALCL bearing t(2;5)(p23;q35) and t(8;17)(q24;q25) translocations who had an aggressive clinical course despit...
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