Selective sweeps for recessive alleles and for other modes of dominance.

Abstract excerpt

A selective sweep describes the reduction of linked genetic variation due to strong positive selection. If s is the fitness advantage of a homozygote for the beneficial allele and h its dominance coefficient, it is usually assumed that h=1/2, i.e. the beneficial allele is co-dominant. We complement existing theory for selective sweeps by assuming that h is any value in [0, 1]. We show that genetic diversity...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alleles
• Share to Computer Simulation
• Share to Genes, Recessive