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Article

Pre-treatment with N-acetylcysteine upregulates superoxide dismutase 2 and catalase genes in cadmium-induced oxidative stress in the chick omphalocele model.

Pediatric surgery international - 1 Feb 2011

Doi Takashi, Puri Prem, Bannigan John, Thompson Jennifer

Abstract excerpt

PURPOSE: In the chick embryo, administration of the heavy metal Cadmium (Cd) induces omphalocele phenotype. Cd is a potent inhibitor of antioxidant enzymes and causes accumulation of reactive oxygen species (ROSs) such as hydrogen peroxide. Previous work with the Cd chick model has demonstrated t...

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Source

Identifiers

PMID: 21069346
DOI: 10.1007/s00383-010-2794-z

Genes

CAT
SOD2
GPX4
SOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21069346-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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