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Article

Early emergence of an H275Y mutation in a hematopoietic cell transplant recipient treated with intravenous peramivir.

Transplant infectious disease : an official journal of the Transplantation Society - 1 Dec 2010

Renaud C, Pergam S A, Polyak C, Jain R, Kuypers J, Englund J A, Corey L, Boeckh M J

Abstract excerpt

Oseltamivir resistance in pandemic 2009 influenza A/H1N1 is caused by the neuraminidase mutation H275Y. This mutation has also been associated with in vitro resistance to peramivir, but few clinical cases have been described to date. Using allele-specific real-time reverse transcriptase polymerase chain reaction assay for the H275Y mutation, we were able to identify resistant H1N1 in a hematopoietic cell...

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Identifiers

PMID: 21062390
DOI: 10.1111/j.1399-3062.2010.00582.x
PMCID: PMC3024056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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