Article
The role of BRCA mutation testing in determining breast cancer therapy.
Nature reviews. Clinical oncology - 1 Dec 2010
Trainer Alison H, Lewis Craig R, Tucker Kathy, Meiser Bettina, Friedlander Michael, Ward Robyn L
Abstract excerpt
Landmark discoveries in the field of breast cancer research include the identification of germline BRCA mutations as a cause of hereditary disease, and the use of gene-expression profiling to identify distinct subtypes of breast cancer. These findings, coupled with the availability of rapid germline testing, make it possible to identify a BRCA mutation carrier contemporaneous with a diagnosis of breast cancer....
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