Article
Rate of familial amyotrophic lateral sclerosis: a systematic review and meta-analysis.
Journal of neurology, neurosurgery, and psychiatry - 1 Jun 2011
Byrne Susan, Walsh Cathal, Lynch Catherine, Bede Peter, Elamin Marwa, Kenna Kevin, McLaughlin Russell, Hardiman Orla
Abstract excerpt
BACKGROUND: The population rate of familial amyotrophic lateral sclerosis (FALS) is frequently reported as 10%. However, a systematic review and meta-analysis of the true population based frequency of FALS has never been performed. METHOD: A Medline literature review identified all original articles reporting a rate of FALS. Studies were grouped according to the type of data presented and examined for sources of...
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