Article
The effect of cyclosporin A on proliferation and differentiation-associated antigens of normal human skin xenografted onto nude mice.
Journal of dermatological science - 1 Mar 1990
Kanitakis J, Urabe A, Haftek M, Thivolet J
Abstract excerpt
Cyclosporin A (CsA) has been shown to inhibit, in vitro, the proliferation of cultured normal and neoplastic keratinocytes and to exert also in vivo an antiproliferative effect on keratinocytes of normal human skin xenografted onto nude mice. To gain further insight into the effects of CsA on hum...
Topics
- Animals
- Antigens, Differentiation
- Bromodeoxyuridine
- Cell Division
- Cyclosporins
- Dose-Response Relationship, Drug
- ErbB Receptors
- Female
- Filaggrin Proteins
- Humans
- Immunohistochemistry
- Intermediate Filament Proteins
- Ki-67 Antigen
- Lectins
- Mice
- Mice, Nude
- Nuclear Proteins
- Peanut Agglutinin
