Article
Molecular cloning of two novel mucin-like genes in the disease-susceptibility locus for diffuse panbronchiolitis.
Human genetics - 1 Feb 2011
Hijikata Minako, Matsushita Ikumi, Tanaka Goh, Tsuchiya Tomoko, Ito Hideyuki, Tokunaga Katsushi, Ohashi Jun, Homma Sakae, Kobashi Yoichiro, Taguchi Yoshio, Azuma Arata, Kudoh Shoji, Keicho Naoto
Abstract excerpt
Diffuse panbronchiolitis (DPB) is a rare complex genetic disease affecting East Asians and is strongly associated with the class I human leukocyte antigens (HLA)-B54 in Japanese and HLA-A11 in Koreans. We recently showed that an HLA-associated major susceptibility gene for DPB is probably located within the 200 kb in the class I region 300 kb telomeric of the HLA-B locus on the chromosome 6p21.3. We cloned two...
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