Article
Fine localization of a major disease-susceptibility locus for diffuse panbronchiolitis.
American journal of human genetics - 1 Feb 2000
Keicho N, Ohashi J, Tamiya G, Nakata K, Taguchi Y, Azuma A, Ohishi N, Emi M, Park M H, Inoko H, Tokunaga K, Kudoh S
Abstract excerpt
Diffuse panbronchiolitis affecting East Asians is strongly associated with the class I human leukocyte antigen (HLA) alleles. Recent observations suggest that a major disease-susceptibility gene may be located between the HLA-B and HLA-A loci in the class I region of the major histocompatibility complex on chromosome 6. To test this possibility, we analyzed 14 polymorphic markers in 92 Japanese patients and 93...
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