Article
Glycosylation genes expressed in seam cells determine complex surface properties and bacterial adhesion to the cuticle of Caenorhabditis elegans.
Genetics - 1 Jan 2011
Gravato-Nobre Maria J, Stroud Dave, O'Rourke Delia, Darby Creg, Hodgkin Jonathan
Abstract excerpt
The surface of the nematode Caenorhabditis elegans is poorly understood but critical for its interactions with the environment and with pathogens. We show here that six genes (bus-2, bus-4, and bus-12, together with the previously cloned srf-3, bus-8, and bus-17) encode proteins predicted to act in surface glycosylation, thereby affecting disease susceptibility, locomotory competence, and sexual recognition....
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