Article
Stability of the high on-treatment platelet reactivity phenotype over time in clopidogrel-treated patients.
Thrombosis and haemostasis - 1 Jan 2011
Jaitner Juliane, Stegherr Julia, Morath Tanja, Braun Siegmund, Bernlochner Isabell, Schömig Aalbert, Kastrati Adnan, Sibbing Dirk
Abstract excerpt
Interindividual response variability to clopidogrel treatment is a well established phenomenon. In recent studies and ongoing large-scale trials where patients with high on-treatment platelet reactivity (HPR) to clopidogrel are being randomised to an intensified antiplatelet treatment, confirmation of the HPR phenotype is based on one single platelet function assessment. The stability of the HPR phenotype over...
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