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Full COLD-PCR Protocol for Noninvasive Prenatal Diagnosis of Genetic Diseases

26 Oct 2010

Abstract excerpt

To the Editor: After the discovery of fetal DNA in maternal plasma, investigators reported different strategies for the noninvasive prenatal diagnosis of genetic diseases (1). Despite the advances in improving the analytical sensitivity of methods, distinguishing between fetal and maternal sequences remains very challenging, and the field of noninvasive prenatal diagnosis of genetic diseases has yet to attain a...

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PMID: 20974797
DOI: 10.1373/clinchem.2010.155671

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