Article
Cracking the Toll-like receptor code in fungal infections.
Expert review of anti-infective therapy - 1 Oct 2010
Cunha Cristina, Romani Luigina, Carvalho Agostinho
Abstract excerpt
Innate control of fungal infection requires the specific recognition of invariant fungal molecular structures by a variety of innate immune receptors, including Toll-like receptors. In addition to the role in inducing protective immune responses, Toll-like receptor engagement may paradoxically favor fungal infections, by inducing inflammatory pathology and impairing antifungal immunity. Although the dissection of...
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