Article
Assessment of genetic ancestry and population substructure in Costa Rica by analysis of individuals with a familial history of mental disorder.
Annals of human genetics - 1 Nov 2010
Segura-Wang Maia, Raventós Henriette, Escamilla Michael, Barrantes Ramiro
Abstract excerpt
The population of Costa Rica has been considered valuable for locating susceptibility genes of complex disorders because of historical events and a gradual admixture process. We present an assessment of 426 unrelated individuals with a familial history of mental disorder and with ancestors born in the Central Valley, genotyped at 730 microsatellites to evaluate genetic diversity, ancestry, and substructure at the...
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