Article
Personalized medicine for non-small-cell lung cancer.
Expert review of anticancer therapy - 1 Oct 2010
Mok Tony S, Zhou Qing, Leung Linda, Loong Herbert H
Abstract excerpt
Non-small-cell lung cancer (NSCLC) is a heterogeneous illness associated with a high mortality rate. Personalized therapy may improve treatment outcomes by identification of a specific genotypic anomaly and target-specific therapy. The most significant development in recent years was the discovery of activated EGF receptor (EGFR) mutations at exons 19 and 21. Patients with EGFR mutations respond dramatically to...
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