Article
Alterations of the pilQ gene in Neisseria gonorrhoeae are unlikely contributors to decreased susceptibility to ceftriaxone and cefixime in clinical gonococcal strains.
The Journal of antimicrobial chemotherapy - 1 Dec 2010
Whiley David M, Jacobsson Susanne, Tapsall John W, Nissen Michael D, Sloots Theo P, Unemo Magnus
Abstract excerpt
OBJECTIVES: Gonorrhoea remains a global public health problem and the treatment options are diminishing through the emergence of gonococci resistant to most antimicrobials. Previous in vitro studies have indicated a role for Neisseria gonorrhoeae pilQ alterations in conferring resistance to antimicrobials, including penicillin. In this study, we investigated whether pilQ polymorphisms were associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
