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Article

Association of Neisseria gonorrhoeae genogroups and specific PBP2/MtrR/PorB mutation patterns with susceptibility to penicillin in a susceptible gonococcal population.

The Journal of antimicrobial chemotherapy - 1 Oct 2018

Thakur Sidharath D, Levett Paul N, Horsman Gregory B, Dillon Jo-Anne R

Abstract excerpt

Objectives: To ascertain whether the antimicrobial susceptibility of Neisseria gonorrhoeae isolates with differing susceptibilities to penicillin is associated with genogroups (GGs) and combined mutation patterns in PBP2 (penA), the multiple transfer resistance repressor (MtrR; mtrR) and porin B (PorB; porB). Methods: The susceptibility of 146 clinical N. gonorrhoeae isolates to penicillin was determined using...

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PMID: 29992304
DOI: 10.1093/jac/dky233

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