Article
In utero life and epigenetic predisposition for disease.
Advances in genetics - 1 Jan 2010
Thornburg Kent L, Shannon Jackilen, Thuillier Philippe, Turker Mitchell S
Abstract excerpt
Regulatory regions of the human genome can be modified through epigenetic processes during prenatal life to make an individual more likely to suffer chronic diseases when they reach adulthood. The modification of chromatin and DNA contributes to a larger well-documented process known as "programming" whereby stressors in the womb give rise to adult onset diseases, including cancer. It is now well known that death...
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