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Article

Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models

6 Oct 2010

Abstract excerpt

BACKGROUND AND AIMS: Increased efficiency of energy harvest, due to alterations in the gut microbiota (increased Firmicutes and decreased Bacteroidetes), has been implicated in obesity in mice and humans. However, a causal relationship is unproven and contributory variables include diet, genetics and age. Therefore, we explored the effect of a high-fat (HF) diet and genetically determined obesity (ob/ob) for...

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PMID: 20926643
DOI: 10.1136/gut.2010.215665

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