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Article

Combination of HOXB4 and Delta-1 ligand improves expansion of cord blood cells.

Blood - 23 Dec 2010

Watts Korashon L, Delaney Colleen, Humphries R Keith, Bernstein Irwin D, Kiem Hans-Peter

Abstract excerpt

Umbilical cord blood (UCB) is an attractive cell source for hematopoietic cell transplantation (HCT). Here we examine whether the combination of homeobox B4 (HOXB4) and Delta-1 ligand (DL) synergize when used together. Monkey and human UCB CD34(+) cells were transduced with a HOXB4-expressing gammaretroviral vector and cultured with DL. Individual and combined effects of HOXB4 and DL were assessed by...

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Source

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Identifiers

PMID: 20921340
DOI: 10.1182/blood-2010-05-286062
PMCID: PMC3031382

Genes

HOXB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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