Article
PSA and beyond: the past, present, and future of investigative biomarkers for prostate cancer.
TheScientificWorldJournal - 1 Oct 2010
Tosoian Jeffrey, Loeb Stacy
Abstract excerpt
The discovery of prostate-specific antigen (PSA) as a biomarker represented a major discovery in the early diagnosis and monitoring of prostate cancer. However, the use of PSA is limited by the lack of specificity and an inability to differentiate indolent from life-threatening disease reliably at the time of diagnosis. A multitude of studies have aimed to improve the performance of PSA as well as identify...
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