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Volatile Anesthetics Modulate Gene Expression in Breast and Brain Tumor Cells

2 Oct 2010

Abstract excerpt

Gene expression is increasingly used for diagnostic, prognostic, and therapeutic purposes in clinical practice. We tested the hypothesis that volatile anesthetics (VA) affect gene expression of tumor cells. Cells from the neuronal cell line SH-SY5Y and from the breast cell line MCF-7 were exposed ex vivo to enflurane, isoflurane, desflurane, halothane, sevoflurane, or nitrous oxide. Microarray gene expression...

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PMID: 20889943
DOI: 10.1213/ane.0b013e3181fa3533

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