Article
Antigenic drift of Orientia tsutsugamushi in South Korea as identified by the sequence analysis of a 56-kDa protein-encoding gene.
The American journal of tropical medicine and hygiene - 1 Oct 2010
Park Sang-Won, Lee Chi Kug, Kwak Yee Gyung, Moon Chisook, Kim Baek-Nam, Kim Eu Suk, Kang Jae Myung, Lee Chang-Seop
Abstract excerpt
This study was performed to determine the nationwide antigenic diversity of Orientia tsutsugamushi in South Korea. Sequence analysis was performed around variable domains I and II of a 56-kDa protein-encoding gene. We used eschar to overcome the disadvantages of conventional serotyping. The serological passive hemagglutination assay (PHA) was assessed based on the genotyping results. We analyzed 153 isolates from...
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