Article
Phosphorylation of p37 is important for Golgi disassembly at mitosis.
Biochemical and biophysical research communications - 5 Nov 2010
Kaneko Yayoi, Tamura Kaori, Totsukawa Go, Kondo Hisao
Abstract excerpt
In mammals, the Golgi apparatus is disassembled at early mitosis and reassembled at the end of mitosis. For Golgi disassembly, membrane fusion needs to be blocked. Golgi biogenesis requires two distinct p97ATPase-mediated membrane fusion, the p97/p47 and p97/p37 pathways. We previously reported that p47 phosphorylation on Serine-140 by Cdc2 results in mitotic inhibition of the p97/p47 pathway [11]. In this study,...
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