Article
Molecular characterization, distribution, and dynamics of hepatitis C virus genotypes in blood donors in Colombia.
Journal of medical virology - 1 Nov 2010
Mora Mónica Viviana Alvarado, Romano Camila Malta, Gomes-Gouvêa Michele Soares, Gutiérrez Maria Fernanda, Carrilho Flair José, Pinho João Renato Rebello
Abstract excerpt
Hepatitis C virus (HCV) is a frequent cause of acute and chronic hepatitis and a leading cause for cirrhosis of the liver and hepatocellular carcinoma. HCV is classified in six major genotypes and more than 70 subtypes. In Colombian blood banks, serum samples were tested for anti-HCV antibodies using a third-generation ELISA. The aim of this study was to characterize the viral sequences in plasma of 184 volunteer...
Topics
- Adult
- Bayes Theorem
- Blood Donors
- Colombia
- Female
- Genotype
- Hepacivirus
- Hepatitis C
- Hepatitis C Antibodies
- Humans
- Male
- Phylogeny
- Polymerase Chain Reaction
- Prevalence
- Sequence Analysis, DNA
