Article
A system for the analysis of BKV non-coding control regions: application to clinical isolates from an HIV/AIDS patient.
Virology - 25 Nov 2010
Broekema Nicole M, Abend Johanna R, Bennett Shauna M, Butel Janet S, Vanchiere John A, Imperiale Michael J
Abstract excerpt
The human polyomavirus BK virus (BKV) is an important opportunistic pathogen whose disease prevalence continues to increase with the growing immunocompromised population. To date, the major determinant of replication in cell culture has not been formally proven. BKV exists as archetype virus and rearranged variants, which are classified based on the DNA sequence of their non-coding control regions (NCCRs). The...
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