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Enhanced Molecular Typing of<i>Treponema pallidum</i>: Geographical Distribution of Strain Types and Association with Neurosyphilis

24 Sept 2010

Abstract excerpt

BACKGROUND: Strain typing is a tool for determining the diversity and epidemiology of infections. METHODS: Treponema pallidum DNA was isolated from 158 patients with syphilis from the United States, China, Ireland, and Madagascar and from 15 T. pallidum isolates. Six typing targets were assessed: (1) the number of 60‐bp repeats in the acidic repeat protein gene, (2) restriction fragment length polymorphism (RFLP)...

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PMID: 20868271
DOI: 10.1086/656533

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