Article
Functionally informative tag SNP selection using a Pareto-optimal approach.
Advances in experimental medicine and biology - 1 Jan 2010
Lee Phil Hyoun, Jung Jae-Yoon, Shatkay Hagit
Abstract excerpt
Selecting a representative set of single nucleotide polymorphism (SNP) markers for facilitating association studies is an important step to uncover the genetic basis of human disease. Tag SNP selection and functional SNP selection are the two main approaches for addressing the SNP selection problem. However, little was done so far to effectively combine these distinct and possibly competing approaches. Here, we...
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