Article
Brain alteration in a Nude/SCID fetus carrying FOXN1 homozygous mutation.
Journal of the neurological sciences - 15 Nov 2010
Amorosi Stefania, Vigliano Ilaria, Del Giudice Ennio, Panico Luigi, Maruotti Giuseppe M, Fusco Anna, Quarantelli Mario, Ciccone Carla, Ursini Matilde V, Martinelli Pasquale, Pignata Claudio
Abstract excerpt
A critical role of the FOX transcription factors in the development of different tissues has been shown. Among these genes, FOXN1 encodes a protein whose alteration is responsible for the Nude/SCID phenotype. Recently, our group reported on a human Nude/SCID fetus, which also had severe neural tu...
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