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Article

Evidence for a predisposing background for CAG expansion leading to HTT mutation in a Chinese population.

Journal of the neurological sciences - 15 Nov 2010

Ma Mingyi, Yang Yuan, Shang Huifang, Su Dan, Zhang Hao, Ma Yongxin, Liu Yunqiang, Tao Dachang, Zhang Sizhong

Abstract excerpt

OBJECTIVE: To investigate the predisposing background for the instability of CAG expansions of the HTT gene in a Chinese population. METHODS: Genotyping and haplotyping of CAG and CCG repeats of the HTT gene were carried out in 32 unrelated HD patients and 95 non-HD control individuals of Han origin, using capillary electrophoresis and DNA sequencing. The frequencies of different CCG repeats were compared between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20864123
DOI: 10.1016/j.jns.2010.08.024

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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