Article
Association study of tumor necrosis factor receptor type 2 M196R and toll-like receptor 2 Arg753Gln polymorphisms with acne vulgaris in a Chinese Han ethnic group.
Dermatology (Basel, Switzerland) - 1 Jan 2010
Tian Li-Ming, Xie Hong-Fu, Yang Ting, Hu Yao-Hua, Li Ji, Wang Wei-Zhen
Abstract excerpt
BACKGROUND: Inflammatory cytokines such as tumor necrosis factor receptor 2 (TNFR2) and Toll-like receptor 2 (TLR2) are the main responsible mediators of inflammatory acne. Factors affecting their production may possibly influence the degree of inflammatory response and hence may account for the clinical severity of acne. However, the roles of TNFR2 and TLR2 in the pathophysiology of acne vulgaris are poorly...
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