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Article

The polymorphism -2548G/A in leptin and severity of chronic obstructive pulmonary disease.

International journal of immunogenetics - 1 Feb 2011

Ye X-W, Xiao M, Ye J, Zhang X-Y, Xiao J, Feng Y-L, Wen F-Q

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease characterized by airway obstruction that is not fully reversible, and there is evidence of a hereditary component in COPD. We aimed to determine whether the polymorphisms -2548G/A of leptin (LEP) gene were associated with COPD and its severity in Chinese. A total of 456 subjects with COPD and 422 healthy controls from West China...

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Source

Identifiers

PMID: 20854423
DOI: 10.1111/j.1744-313X.2010.00968.x

Genes

LEP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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