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Article

A transient epidermolysis bullosa simplex-like phenotype associated with bexarotene treatment in a G138E KRT5 heterozygote.

Journal of cutaneous pathology - 1 Nov 2010

Trufant Joshua W, Kreizenbeck Gretchen M, Carlson Kacie R, Muthusamy Viswanathan, Girardi Michael, Bosenberg Marcus W

Abstract excerpt

Basal keratinocyte lysis is the hallmark histopathological finding of epidermolysis bullosa simplex (EBS), a group of rare heritable mechanobullous disorders characterized by intraepidermal blister formation and skin fragility. Over 100 mutations, found predominantly in the genes encoding keratins 5 and 14 (KRT5, KRT14), have been described to account for a variety of clinical subtypes. EBS with mottled...

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Source

Identifiers

PMID: 20849457
DOI: 10.1111/j.1600-0560.2010.01557.x

Genes

KRT5
KRT14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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