Article
Impact of CYP2D6*4 genotype on progression free survival in tamoxifen breast cancer treatment.
Current medical research and opinion - 1 Nov 2010
Stingl Julia Carolin, Parmar Sumit, Huber-Wechselberger Ariana, Kainz Alexander, Renner Wilfried, Seeringer Angela, Brockmöller Jürgen, Langsenlehner Uwe, Krippl Peter, Haschke-Becher Elisabeth
Abstract excerpt
OBJECTIVE: The cytochrome P450 2D6 (CYP2D6) polymorphism was reported to have a significant impact on outcome of tamoxifen treatment in estrogen receptor positive breast cancer patients. The objective of this study was to explore the effect of the CYP2D6*4 polymorphism on tamoxifen treatment outc...
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