Article
Genetic algorithms and their application to in silico evolution of genetic regulatory networks.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Knabe Johannes F, Wegner Katja, Nehaniv Chrystopher L, Schilstra Maria J
Abstract excerpt
A genetic algorithm (GA) is a procedure that mimics processes occurring in Darwinian evolution to solve computational problems. A GA introduces variation through "mutation" and "recombination" in a "population" of possible solutions to a problem, encoded as strings of characters in "genomes," and allows this population to evolve, using selection procedures that favor the gradual enrichment of the gene pool with...
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